Triaminic Softchew Throat Pain and Cough

Generic Name: acetaminophen, dextromethorphan, and pseudoephedrine (a SEET a MIN oh fen, DEX troe me THOR fan, SOO doe ee FED rin)

Brand Names: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, DayQuil, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu (pseudoephedrine) Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat (pseudoephedrine), Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat (pseudoephedrine)

What is Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, dextromethorphan, and pseudoephedrine is used to treat headache, fever, body aches, cough, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What should I discuss with my healthcare provider before taking Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take acetaminophen, dextromethorphan, and pseudoephedrine if you have:

• 
  

  liver disease, cirrhosis, or a history of alcoholism;

  
  


• 
  

  diabetes;

  
  


• 
  

  glaucoma;

  
  


• 
  

  diabetes;

  
  


• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  enlarged prostate or urination problems;

  
  


• 
  

  pheochromocytoma (an adrenal gland tumor); or

  
  


• 
  

  cough with mucus, or cough caused by emphysema or chronic bronchitis.

  
  

It is not known whether acetaminophen, dextromethorphan, and pseudoephedrine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant. Acetaminophen, dextromethorphan, and pseudoephedrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

The chewable tablet must be chewed thoroughly before you swallow it.

Dissolve one packet of the powder in at least 4 ounces of water. Stir this mixture and drink all of it right away.

Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen.

Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. chest pain, fast, slow, or uneven heart rate; Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  chest pain, fast, slow, or uneven heart rate;

  
  


• 
  

  severe dizziness, feeling like you might pass out;

  
  


• 
  

  mood changes, confusion, hallucinations;

  
  


• 
  

  tremor, seizure (convulsions);

  
  


• 
  

  fever;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

  
  


• 
  

  nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

  
  

Less serious side effects may include:

• 
  

  dizziness, weakness;

  
  


• 
  

  mild headache;

  
  


• 
  

  mild nausea, diarrhea, upset stomach;

  
  


• 
  

  dry mouth, nose, or throat;

  
  


• 
  

  feeling nervous, restless, irritable, or anxious; or

  
  


• 
  

  sleep problems (insomnia).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Triaminic Softchew Throat Pain and Cough (acetaminophen, dextromethorphan, and pseudoephedrine)?

Ask a doctor or pharmacist if it is safe for you to take this medicine if you are also using any of the following drugs:

• 
  

  leflunomide (Arava);

  
  


• 
  

  tapentadol (Nucynta);

  
  


• 
  

  an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;

  
  


• 
  

  an antidepressant;

  
  


• 
  

  birth control pills or hormone replacement therapy;

  
  


• 
  

  blood pressure medication;

  
  


• 
  

  cancer medicine;

  
  


• 
  

  cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;

  
  


• 
  

  gout or arthritis medications (including gold injections);

  
  


• 
  

  HIV/AIDS medication;

  
  


• 
  

  medicines to treat psychiatric disorders;

  
  


• 
  

  migraine headache medicine;

  
  


• 
  

  an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or

  
  


• 
  

  seizure medication.

  
  

This list is not complete and other drugs may interact with acetaminophen, dextromethorphan, and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Triaminic Softchew Throat Pain and Cough resources

• Triaminic Softchew Throat Pain and Cough Side Effects (in more detail)
• Triaminic Softchew Throat Pain and Cough Use in Pregnancy & Breastfeeding
• Triaminic Softchew Throat Pain and Cough Drug Interactions
• Triaminic Softchew Throat Pain and Cough Support Group
• 1 Review for Triaminic Softchew Throat Pain and Cough - Add your own review/rating

• DayQuil Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Triaminic Softchew Throat Pain and Cough with other medications

• Cold Symptoms

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, dextromethorphan, and pseudoephedrine.

See also: Triaminic Softchew Throat Pain and Cough side effects (in more detail)

Trifluridine Drops

Pronunciation: trye-FLURE-i-deen
Generic Name: Trifluridine
Brand Name: Viroptic

Trifluridine Drops are used for:

Treating herpes eye infection.

Trifluridine Drops are an antiviral. It works by killing sensitive viruses.

Do NOT use Trifluridine Drops if:

• you are allergic to any ingredient in Trifluridine Drops

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trifluridine Drops:

Some medical conditions may interact with Trifluridine Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Trifluridine Drops. Because little, if any, of Trifluridine Drops are absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trifluridine Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trifluridine Drops:

Use Trifluridine Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use Trifluridine Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.


• Contact your doctor for instructions on using your contact lenses while using Trifluridine Drops.


• To clear up your infection completely, continue using Trifluridine Drops for the full course of treatment even if you feel better in a few days.


• If you miss a dose of Trifluridine Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Trifluridine Drops.

Important safety information:

• Do not exceed the recommended dose or use Trifluridine Drops for longer than prescribed without checking with your doctor.


• If your condition does not improve within 7 days or if it becomes worse, check with your doctor.


• Do not use Trifluridine Drops for other eye problems without first checking with your doctor.


• It is important to use Trifluridine Drops for the full course of treatment. Failure to do so may decrease the effectiveness of Trifluridine Drops and increase the risk that the virus will no longer be sensitive to Trifluridine Drops and will not be able to be treated by this or certain other antivirals in the future.


• Use Trifluridine Drops with extreme caution in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Trifluridine Drops during pregnancy. It is unknown if Trifluridine Drops are excreted in breast milk. If you are or will be breast-feeding while you are using Trifluridine Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Trifluridine Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Temporary burning or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); new or worsening eye irritation or pain; red or bloodshot eyes; swelling of the eye or eyelid; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Trifluridine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Trifluridine Drops:

Store Trifluridine Drops in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Keep Trifluridine Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Trifluridine Drops, please talk with your doctor, pharmacist, or other health care provider.


• Trifluridine Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Trifluridine Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Trifluridine resources

• Trifluridine Side Effects (in more detail)
• Trifluridine Use in Pregnancy & Breastfeeding
• Trifluridine Support Group
• 0 Reviews for Trifluridine - Add your own review/rating

Compare Trifluridine with other medications

• Herpetic Keratitis

Synalar

Generic Name: fluocinolone (Topical application route)

floo-oh-SIN-oh-lone a-SEET-oh-nide

Commonly used brand name(s)

In the U.S.

• Capex


• Derma-Smoothe/FS


• Synalar

In Canada

• Fluoderm Mild Cream


• Fluoderm Mild Ointment


• Fluoderm Regular Cream


• Fluoderm Regular Ointment


• Fluolar Mild


• Fluolar Regular


• Fluonide Mild-Cream


• Synalar Mild


• Synalar Regular


• Synamol

Available Dosage Forms:

• Cream


• Solution


• Shampoo


• Oil


• Ointment


• Lotion


• Gel/Jelly


• Kit

Therapeutic Class: Corticosteroid, Intermediate

Pharmacologic Class: Fluocinolone

Uses For Synalar

Fluocinolone topical is used to relieve redness, itching, swelling, or other discomfort caused by skin conditions. Fluocinolone scalp oil is used to treat psoriasis of the scalp, and fluocinolone shampoo for seborrheic dermatitis of the scalp. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor's prescription.

Before Using Synalar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluocinolone topical in the pediatric population. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. For the body oil form, safety and efficacy in children 3 months of age and younger have not been established.

Geriatric

No information is available on the relationship of age to the effects of fluocinolone topical in geriatric patients.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing's syndrome (adrenal gland disorder) or


• Diabetes or


• Hyperglycemia (high blood sugar) or


• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection of the skin at or near the place of application or


• Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

Proper Use of fluocinolone

This section provides information on the proper use of a number of products that contain fluocinolone. It may not be specific to Synalar. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

To use cream, ointment, solution, and body oil:

• Wash your hands with soap and water before and after using this medicine.


• Apply a thin layer of this medicine to the affected area of the skin or scalp. Rub it in gently.


• Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.


• If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.


• If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

To use shampoo:

• Wash your hands with soap and water before and after using this medicine.


• Wet hair and scalp thoroughly.


• Shake the container well, and apply about an ounce of the shampoo to the scalp area.


• Work the shampoo into a lather, and leave on the scalp for 5 minutes.


• Wash hair and scalp thoroughly with water.

To use scalp oil:

• Wash your hands with soap and water before and after using this medicine.


• Wet hair and scalp thoroughly.


• Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently.


• Cover the scalp with the supplied shower cap overnight for at least 4 hours.


• Wash hair with regular shampoo and clean well.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For redness, itching, and swelling of the skin:
  
  • For topical dosage form (cream, ointment, and solution):
    
    • Adults—Apply to the affected areas of the skin three to four times a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For topical dosage form (body oil):
    
    • Adults—Apply to the affected areas of the skin three times a day for up to 2 weeks.
    
    
    • Children 3 months of age and older—Apply to the affected areas two times a day for up to 4 weeks.
    
    
  
  

• For seborrheic dermatitis:
  
  • For topical dosage form (shampoo):
    
    • Adults—Use on the scalp area once a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

• For scalp psoriasis:
  
  • For topical dosage form (scalp oil):
    
    • Adults—Apply to the affected areas of the scalp and leave overnight.
    
    
    • Children 2 years of age and older—Apply to the affected areas 2 times a day for up to 4 weeks.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Synalar

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Synalar Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Body aches or pain


• congestion


• cough


• dryness or soreness of the throat


• fever


• headache


• hoarseness


• lightening of normal skin color


• lightening of treated areas of dark skin


• sore throat


• stuffy or runny nose


• tender, swollen glands in the neck


• trouble swallowing


• unusual tiredness or weakness


• voice changes

Less common

• Acne or pimples


• accumulation of pus


• blistering, crusting, irritation, itching, or reddening of the skin


• burning, itching, and pain in hairy areas, or pus at the root of the hair


• burning and itching of the skin with pinhead-sized red blisters


• change in hearing


• cracked, dry, scaly skin


• diarrhea


• dry skin


• earache or pain in the ear


• ear drainage


• flushing or redness of the skin


• darkening of the skin


• itching, scaling, severe redness, soreness, or swelling of the skin


• itchy, raised, round, smooth, skin-colored bumps found on just one area of the body


• ooze thick white fluid


• raised, dark red, wart-like spots on skin, especially when used on the face


• redness or swelling in the ear


• skin irritation


• skin rash, encrusted, scaly and oozing


• spots on your skin resembling a blister or pimple


• swelling


• swollen, red, tender area of infection


• thickened patches of the skin


• vomiting

Incidence not known

• Redness and scaling around the mouth


• thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Changes in skin color


• shiny skin

Incidence not known

• increased hair growth on the forehead, back, arms, and legs


• reddish purple lines on the arms, face, legs, trunk, or groin


• softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Synalar side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Synalar resources

• Synalar Side Effects (in more detail)
• Synalar Use in Pregnancy & Breastfeeding
• Synalar Drug Interactions
• Synalar Support Group
• 2 Reviews for Synalar - Add your own review/rating

• Synalar Consumer Overview


• Synalar Prescribing Information (FDA)


• Synalar Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Capex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


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Sulfonamide

Class Name: sulfonamide (Oral route)

Commonly used brand name(s)

In the U.S.

• Azulfidine


• Azulfidine Entabs


• Diamox Sequels


• Gantrisin Pediatric


• Sulfazine


• Sulfazine EC


• Truxazole


• Zonegran

In Canada

• Alti-Sulfasalazine


• Salazopyrin

Available Dosage Forms:

• Tablet


• Capsule, Extended Release


• Syrup


• Suspension


• Capsule


• Tablet, Enteric Coated

Uses For This Medicine

Sulfonamides or sulfa medicines are used to treat infections. They will not work for colds, flu, or other virus infections.

Sulfonamides are available only with your doctor's prescription.

Before Using This Medicine

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Sulfonamides should not be given to infants under 2 months of age unless directed by the child's doctor, because they may cause unwanted effects.

Geriatric

Elderly people are especially sensitive to the effects of sulfonamides. Severe skin problems and blood problems may be more likely to occur in the elderly. These problems may also be more likely to occur in patients who are taking diuretics (water pills) along with this medicine.

Pregnancy

Studies have not been done in pregnant women. However, studies in mice, rats, and rabbits have shown that some sulfonamides cause birth defects, including cleft palate and bone problems. Sulfonamides are not recommended for use at the time of labor and delivery. These medicines may cause unwanted effects in the baby.

Breast Feeding

Sulfonamides pass into the breast milk. This medicine is not recommended for use during breast-feeding. It may cause liver problems, anemia, and other unwanted effects in nursing babies, especially those with glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

• Bepridil


• Cisapride


• Dofetilide


• Levomethadyl


• Mesoridazine


• Pimozide


• Terfenadine


• Thioridazine

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Acenocoumarol


• Ajmaline


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Aprindine


• Arsenic Trioxide


• Astemizole


• Azimilide


• Bretylium


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Clarithromycin


• Desipramine


• Dibenzepin


• Digitalis


• Disopyramide


• Dolasetron


• Doxepin


• Droperidol


• Enflurane


• Erythromycin


• Flecainide


• Fluconazole


• Fluoxetine


• Foscarnet


• Gemifloxacin


• Halofantrine


• Haloperidol


• Halothane


• Hydroquinidine


• Ibutilide


• Imipramine


• Isoflurane


• Isradipine


• Ketorolac


• Levomethadyl


• Lidoflazine


• Lorcainide


• Mefloquine


• Metformin


• Methotrexate


• Naproxen


• Nortriptyline


• Octreotide


• Pentamidine


• Pirmenol


• Prajmaline


• Probucol


• Procainamide


• Prochlorperazine


• Propafenone


• Proscillaridin


• Pyrimethamine


• Quetiapine


• Quinidine


• Riluzole


• Risperidone


• Sematilide


• Sertindole


• Sotalol


• Spiramycin


• Sultopride


• Tedisamil


• Telithromycin


• Trifluoperazine


• Trimipramine


• Vasopressin


• Warfarin


• Zotepine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use your medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Anemia or other blood problems or


• Glucose-6-phosphate dehydrogenase (G6PD) deficiency—Patients with these problems may have an increase in side effects affecting the blood.

• Kidney disease or


• Liver disease—Patients with kidney and/or liver disease may have an increased chance of side effects.

• Porphyria—This medicine may bring on an attack of porphyria.

Proper Use of This Medicine

Sulfonamides should not be given to infants less than 2 months of age unless directed by the patient's doctor because sulfonamides may cause serious unwanted effects.

Sulfonamides are best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects of sulfonamides.

For patients taking the oral liquid form of this medicine:

• Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times day and night. If you need help in planning the best times to take your medicine, check with your health care professional.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For sulfadiazine


• For oral dosage form (tablet):
  
  • For bacterial or protozoal infections:
    
    • Adults and teenagers—2 to 4 grams for the first dose, then 1 gram every four to six hours.
    
    
    • Children 2 months of age and older—Dose is based on body weight. The usual dose is 75 milligrams (mg) per kilogram (kg) (34 mg per pound) of body weight for the first dose, then 37.5 mg per kg (17 mg per pound) of body weight every six hours, or 25 mg per kg (11.4 mg per pound) of body weight every four hours.
    
    
    • Children up to 2 months of age—Use is not recommended.
    
    
  
  

• For sulfamethizole


• For oral dosage form (tablets):
  
  • For bacterial infections:
    
    • Adults and teenagers—500 milligrams (mg) to 1 gram every six to eight hours.
    
    
    • Children 2 months of age and older—Dose is based on body weight. The usual dose is 7.5 to 11.25 mg per kilogram (kg) (3.4 to 5.1 mg per pound) of body weight every six hours.
    
    
    • Children up to 2 months of age—Use is not recommended.
    
    
  
  

• For sulfamethoxazole


• For oral dosage form (tablets):
  
  • For bacterial or protozoal infections:
    
    • Adults and teenagers—2 to 4 grams for the first dose, then 1 to 2 grams every eight to twelve hours.
    
    
    • Children 2 months of age and older—Dose is based on body weight. The usual dose is 50 to 60 milligrams (mg) per kilogram (kg) (22.7 to 27.3 mg per pound) of body weight for the first dose, then 25 to 30 mg per kg (11.4 to 13.6 mg per pound) of body weight every twelve hours.
    
    
    • Children up to 2 months of age—Use and dose must be determined by your doctor.
    
    
  
  

• For sulfisoxazole


• For oral dosage forms (suspension, syrup, or tablets):
  
  • 
    
    • Adults and teenagers—2 to 4 grams for the first dose, then 750 milligrams (mg) to 1.5 grams every four hours; or 1 to 2 grams every six hours.
    
    
    • Children 2 months of age and older—Dose is based on body weight. The usual dose is 75 mg per kilogram (kg) (34 mg per pound) of body weight for the first dose, then 25 mg per kg (11.4 mg per pound) of body weight every four hours, or 37.5 mg per kg (17 mg per pound) of body weight every six hours.
    
    
    • Children up to 2 months of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using This Medicine

It is very important that your doctor check your progress at regular visits. This medicine may cause blood problems, especially if it is taken for a long time.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Sulfonamides may cause blood problems. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. Dental work should be delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.

Sulfonamides may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

• Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.


• Wear protective clothing, including a hat. Also, wear sunglasses.


• Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.


• Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.


• Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

This medicine may also cause some people to become dizzy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert. If this reaction is especially bothersome, check with your doctor.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Itching


• skin rash

Less common

• Aching of joints and muscles


• difficulty in swallowing


• pale skin


• redness, blistering, peeling, or loosening of skin


• sore throat and fever


• unusual bleeding or bruising


• unusual tiredness or weakness


• yellow eyes or skin

Rare

Some of the above side effects (severe abdominal or stomach cramps and pain, and watery and severe diarrhea, which may also be bloody) may also occur up to several weeks after you stop taking any of these medicines.

• Abdominal or stomach cramps and pain (severe)


• abdominal tenderness


• blood in urine


• diarrhea (watery and severe), which may also be bloody


• greatly increased or decreased frequency of urination or amount of urine


• increased thirst


• lower back pain


• mood or mental changes


• pain or burning while urinating


• swelling of front part of neck

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Increased sensitivity of skin to sunlight

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Diarrhea


• dizziness


• headache


• loss of appetite


• nausea or vomiting


• tiredness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Sorine

Generic Name: sotalol (Oral route)

SOE-ta-lol

Oral route(Tablet)

To minimize the risk of induced arrhythmia, patients initiated or reinitiated on sotalol should be placed for a minimum of three days (on their maintenance dose) in a facility that can provide continuous cardiac resuscitation and ECG monitoring. Creatinine clearance should be calculated prior to dosing. Sotalol marketed under the brand name Betapace(R) is indicated for the treatment of documented life-threatening ventricular arrhythmias. Sotalol marketed under the brand name Betapace AF(R) is indicated for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial flutter (AFIB/AFL)) in patients with symptomatic AFIB/AFL who are currently in sinus rhythm. Betapace(R) and Betapace AF(R) cannot be substituted for each other because of significant differences in labeling (eg, indications, patient package insert, dosing administration, and safety information) .

Commonly used brand name(s)

In the U.S.

• Betapace


• Betapace AF


• Sorine

Available Dosage Forms:

• Tablet

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective

Uses For Sorine

Sotalol is used to control rapid heartbeats and abnormal heart rhythms .

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and at a regular rhythm .

This medicine is available only with your doctor's prescription .

Before Using Sorine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of sotalol in the pediatric population. Safety and efficacy have not been established .

Geriatric

No information is available on the relationship of age to the effects of sotalol in geriatric patients .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Bepridil


• Cisapride


• Dronedarone


• Grepafloxacin


• Levomethadyl


• Mesoridazine


• Pimozide


• Sparfloxacin


• Terfenadine


• Thioridazine


• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Acetazolamide


• Albuterol


• Amiloride


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Apomorphine


• Aprindine


• Arformoterol


• Arsenic Trioxide


• Asenapine


• Astemizole


• Azimilide


• Azithromycin


• Azosemide


• Bambuterol


• Bemetizide


• Bendroflumethiazide


• Benzthiazide


• Bitolterol


• Bretylium


• Broxaterol


• Bumetanide


• Canrenoate


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Chlorthalidone


• Ciprofloxacin


• Citalopram


• Clarithromycin


• Clenbuterol


• Clomipramine


• Clonidine


• Clopamide


• Clozapine


• Colterol


• Crizotinib


• Cyclothiazide


• Dasatinib


• Desipramine


• Dibenzepin


• Diltiazem


• Disopyramide


• Dofetilide


• Dolasetron


• Doxepin


• Dronedarone


• Droperidol


• Enflurane


• Epinephrine


• Erythromycin


• Ethacrynic Acid


• Etozolin


• Fenoldopam


• Fenoterol


• Fenquizone


• Fingolimod


• Flecainide


• Fluconazole


• Fluoxetine


• Formoterol


• Foscarnet


• Furosemide


• Gatifloxacin


• Gemifloxacin


• Granisetron


• Halofantrine


• Haloperidol


• Halothane


• Hexoprenaline


• Hydrochlorothiazide


• Hydroflumethiazide


• Ibutilide


• Iloperidone


• Imipramine


• Indacaterol


• Indapamide


• Isoetharine


• Isoflurane


• Isradipine


• Itraconazole


• Ketoconazole


• Lapatinib


• Levalbuterol


• Levofloxacin


• Lidocaine


• Lidoflazine


• Lopinavir


• Lorcainide


• Lumefantrine


• Mannitol


• Mefloquine


• Metaproterenol


• Methadone


• Metolazone


• Moricizine


• Moxifloxacin


• Nilotinib


• Norfloxacin


• Nortriptyline


• Octreotide


• Ofloxacin


• Ondansetron


• Paliperidone


• Pazopanib


• Pentamidine


• Perflutren Lipid Microsphere


• Pirbuterol


• Piretanide


• Polythiazide


• Posaconazole


• Prilocaine


• Probucol


• Procainamide


• Procaterol


• Prochlorperazine


• Promethazine


• Propafenone


• Protriptyline


• Quetiapine


• Quinethazone


• Quinidine


• Quinine


• Ranolazine


• Reproterol


• Rimiterol


• Risperidone


• Ritodrine


• Salmeterol


• Saquinavir


• Sematilide


• Sertindole


• Sodium Phosphate


• Sodium Phosphate, Dibasic


• Sodium Phosphate, Monobasic


• Solifenacin


• Sorafenib


• Sotalol


• Spiramycin


• Spironolactone


• Sulfamethoxazole


• Sultopride


• Sunitinib


• Tedisamil


• Telavancin


• Telithromycin


• Terbutaline


• Tetrabenazine


• Ticrynafen


• Toremifene


• Torsemide


• Trazodone


• Tretoquinol


• Triamterene


• Trichlormethiazide


• Trifluoperazine


• Trimethoprim


• Trimipramine


• Tulobuterol


• Vandetanib


• Vardenafil


• Vasopressin


• Vemurafenib


• Verapamil


• Voriconazole


• Xipamide


• Zolmitriptan


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abarelix


• Acarbose


• Aceclofenac


• Acemetacin


• Acetohexamide


• Alclofenac


• Alfuzosin


• Amlodipine


• Apazone


• Arbutamine


• Benfluorex


• Benoxaprofen


• Bromfenac


• Bufexamac


• Bunazosin


• Carprofen


• Chlorpropamide


• Clometacin


• Clonixin


• Dexketoprofen


• Diclofenac


• Diflunisal


• Digoxin


• Dipyrone


• Doxazosin


• Droxicam


• Etodolac


• Etofenamate


• Felbinac


• Felodipine


• Fenbufen


• Fenoprofen


• Fentiazac


• Floctafenine


• Flufenamic Acid


• Flurbiprofen


• Gliclazide


• Glimepiride


• Glipizide


• Gliquidone


• Glyburide


• Guar Gum


• Ibuprofen


• Indomethacin


• Indoprofen


• Insulin


• Insulin Aspart, Recombinant


• Insulin Glulisine


• Insulin Lispro, Recombinant


• Isoxicam


• Ketoprofen


• Ketorolac


• Lacidipine


• Lercanidipine


• Lornoxicam


• Manidipine


• Meclofenamate


• Mefenamic Acid


• Meloxicam


• Metformin


• Methyldopa


• Mibefradil


• Miglitol


• Moxisylyte


• Nabumetone


• Naproxen


• Nicardipine


• Nifedipine


• Niflumic Acid


• Nilvadipine


• Nimesulide


• Nimodipine


• Nisoldipine


• Nitrendipine


• Oxaprozin


• Oxyphenbutazone


• Phenoxybenzamine


• Phentolamine


• Phenylbutazone


• Pirazolac


• Piroxicam


• Pirprofen


• Pranidipine


• Prazosin


• Propyphenazone


• Proquazone


• Repaglinide


• St John's Wort


• Sulindac


• Suprofen


• Tamsulosin


• Tenidap


• Tenoxicam


• Terazosin


• Tiaprofenic Acid


• Tolazamide


• Tolbutamide


• Tolmetin


• Trimazosin


• Troglitazone


• Urapidil


• Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Asthma or


• Bradycardia (slow heartbeat) or


• Heart block or


• Heart failure or


• Long QT syndrome (heart rhythm problem)—Should not use in patients with these conditions .

• Diabetes or


• Hyperthyroidism (overactive thyroid) or


• Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat .

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .

• Lung disease (e.g., bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition .

• Sick sinus syndrome (heart rhythm problem)—Use with caution. May make this condition worse .

Proper Use of sotalol

This section provides information on the proper use of a number of products that contain sotalol. It may not be specific to Sorine. Please read with care.

For the first three days, you will receive this medicine in a hospital where your heart rhythm can be monitored .

Do not interrupt or stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For abnormal heart rhythms:
    
    • Adults—At first, 80 milligrams (mg) two times a day. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Sorine

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

Sotalol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing .

This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests .

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests .

Sorine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Blurred vision


• chest pain or discomfort


• confusion


• diarrhea


• difficult or labored breathing


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• fast, slow, irregular, pounding, or racing heartbeat or pulse


• lightheadedness, dizziness, or fainting


• nausea and vomiting


• shortness of breath


• sweating


• swelling of face, fingers, feet, or lower legs


• tightness in chest


• unusual tiredness or weakness


• wheezing

Less common

• Abdominal pain or swelling


• back pain


• black, tarry stools


• blood in eyes


• blood in urine


• body aches or pain


• bruising or purple areas on skin


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• change in consciousness


• cold hands and feet


• cough or hoarseness


• coughing up blood


• decreased alertness


• decreased urine output


• difficulty in speaking


• dilated neck veins


• double vision


• ear congestion


• extreme fatigue


• feeling of warmth or heat


• fever or chills


• flushing or redness of skin, especially on face and neck


• headache


• inability to move arms, legs, or facial muscles


• inability to speak


• irregular breathing


• joint pain or swelling


• loss of voice


• lower back or side pain


• nasal congestion


• nervousness


• noisy breathing


• nosebleeds


• painful, burning, or difficult urination


• pounding in the ears


• runny nose


• slow speech


• sneezing


• sore throat


• troubled breathing


• weight gain

Rare

• Bleeding gums


• fast breathing, sometimes with wheezing


• large amount of fat in the blood


• not able to move


• pinpoint red spots on skin


• sores, ulcers, or white spots on lips or in mouth


• swollen glands


• unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Anxiety


• cold sweats


• coma


• cool, pale skin


• depression


• increased hunger


• nightmares


• no heartbeat


• seizures


• shakiness


• slurred speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Acid or sour stomach


• belching


• difficulty in sleeping


• heartburn


• indigestion


• lack or loss of strength


• pain in arms or legs


• stomach discomfort or upset

Less common

• Abnormal ejaculation


• bloated


• decreased sexual performance or desire


• disturbed color perception


• double vision


• excess air or gas in stomach or intestines


• full feeling


• halos around lights


• loss of appetite


• loss of vision


• mood changes


• night blindness


• overbright appearance of lights


• passing gas


• skin rash


• tunnel vision


• weight changes

Rare

• Crying


• depersonalization


• difficulty in moving


• dysphoria


• euphoria


• feeling of constant movement of self or surroundings


• hair loss, thinning of hair


• increased sensitivity of skin to sunlight


• itching skin


• lack of coordination


• mental depression


• muscle aching or cramping


• muscle pains or stiffness


• paranoia


• quick to react or overreact emotionally


• rapidly changing moods


• redness or other discoloration of skin


• sensation of spinning


• severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Sorine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Sorine resources

• Sorine Side Effects (in more detail)
• Sorine Use in Pregnancy & Breastfeeding
• Drug Images
• Sorine Drug Interactions
• Sorine Support Group
• 0 Reviews for Sorine - Add your own review/rating

• Sorine Prescribing Information (FDA)


• Sorine Concise Consumer Information (Cerner Multum)


• Sotalol Prescribing Information (FDA)


• Betapace MedFacts Consumer Leaflet (Wolters Kluwer)


• Betapace Prescribing Information (FDA)


• Betapace AF Concise Consumer Information (Cerner Multum)


• Betapace AF MedFacts Consumer Leaflet (Wolters Kluwer)


• Betapace AF Prescribing Information (FDA)


• Sotalol Hydrochloride Monograph (AHFS DI)

Compare Sorine with other medications

• Ventricular Arrhythmia

Nicotine Inhaler

Pronunciation: NIK-oh-teen
Generic Name: Nicotine
Brand Name: Nicotrol

Nicotine Inhaler is used for:

Helping you to quit smoking.

Nicotine Inhaler is a smoking deterrent. It works by providing low levels of nicotine, which may help you to quit smoking by lessening the physical signs of withdrawal symptoms.

Do NOT use Nicotine Inhaler if:

• you are allergic to any ingredient in Nicotine Inhaler or to menthol


• you have had a recent heart attack


• you have severe or worsening chest pain or a severely irregular heartbeat


• you continue to smoke, chew tobacco, use snuff, or any other nicotine-containing products

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nicotine Inhaler:

Some medical conditions may interact with Nicotine Inhaler. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have chest pain (eg, angina), heart problems (eg, coronary artery disease, irregular heartbeat), a history of heart attack, high blood pressure, breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD]), an overactive thyroid, an ulcer, a tumor on your adrenal gland (pheochromocytoma), diabetes, kidney or liver problems, or blood vessel problems (eg, Buerger disease, Raynaud phenomena)

Some MEDICINES MAY INTERACT with Nicotine Inhaler. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acetaminophen, adrenergic antagonists (eg, prazosin), beta-blockers (eg, labetalol, propranolol), caffeine, imipramine, insulin, oxazepam, pentazocine, or theophylline because the risk of their side effects may be increased when you stop smoking


• Adrenergic agonists (eg, isoproterenol, phenylephrine) because their effectiveness may be decreased when you stop smoking

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nicotine Inhaler may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nicotine Inhaler:

Use Nicotine Inhaler as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Nicotine Inhaler. Talk to your pharmacist if you have questions about this information.


• Do not exceed 16 cartridges per day.


• Clean the mouthpiece regularly with soap and water.


• If you miss a dose of Nicotine Inhaler, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Nicotine Inhaler.

Important safety information:

• Nicotine Inhaler may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Nicotine Inhaler with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Tell your doctor or dentist that you take Nicotine Inhaler before you receive any medical or dental care, emergency care, or surgery.


• Avoid getting Nicotine Inhaler in your eyes. If you get Nicotine Inhaler in your eyes, wash them out immediately with cool tap water.


• Do not smoke or use tobacco products while you are using Nicotine Inhaler.


• Nicotine Inhaler should be used as part of a larger program to help you stop smoking. If you need help choosing a program, talk with your health care provider.


• Do NOT use Nicotine Inhaler for longer than 6 months. If you still feel the need to use Nicotine Inhaler after 6 months, check with your doctor.


• Diabetes patients - Nicotine Inhaler may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Use Nicotine Inhaler with caution in the ELDERLY; they may be more sensitive to its effects.


• Use Nicotine Inhaler with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Nicotine Inhaler may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nicotine Inhaler while you are pregnant. Nicotine Inhaler is found in breast milk. If you are or will be breast-feeding while you use Nicotine Inhaler, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, some people develop a need to continue taking Nicotine Inhaler. This is known as DEPENDENCE or addiction.

Do not suddenly stop taking Nicotine Inhaler without your doctor's approval. Stopping Nicotine Inhaler suddenly may cause serious WITHDRAWAL symptoms. These may include anxiety; depression; dizziness; fatigue; muscle aches; sleep problems.

Possible side effects of Nicotine Inhaler:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; coughing; diarrhea; flu-like symptoms; headache; hiccups; indigestion; mouth or throat irritation; muscle aches; nausea; pain in the jaw and neck; runny nose; taste changes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal skin sensations; chest pain; depression; fever; irregular or fast heartbeat; pounding in the chest; severe dizziness or headache; shortness of breath.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Nicotine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; confusion; diarrhea; difficulty breathing; dizziness; excessive drooling; fainting; headache; hearing and vision problems; nausea; rapid, weak, or irregular heartbeat; seizures; stomach pain; sweating; tremor; vomiting; weakness.

Proper storage of Nicotine Inhaler:

Store Nicotine Inhaler at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Store the mouthpiece and cartridges in the plastic case provided. Do not store in the bathroom. Keep Nicotine Inhaler out of the reach of children and away from pets.

General information:

• If you have any questions about Nicotine Inhaler, please talk with your doctor, pharmacist, or other health care provider.


• Nicotine Inhaler is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nicotine Inhaler. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nicotine resources

• Nicotine Side Effects (in more detail)
• Nicotine Use in Pregnancy & Breastfeeding
• Nicotine Drug Interactions
• Nicotine Support Group
• 42 Reviews for Nicotine - Add your own review/rating

Compare Nicotine with other medications

• Smoking Cessation

Kepivance

Pronunciation: pal-ee-FER-min
Generic Name: Palifermin
Brand Name: Kepivance

Kepivance is used for:

Reducing and treating mouth sores in patients who are receiving chemotherapy and radiation to treat lymphoma and other blood-related cancers.

Kepivance is a protein, keratinocyte growth factor. It works by increasing cell growth and healing of skin tissue.

Do NOT use Kepivance if:

• you are allergic to any ingredient in Kepivance

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kepivance:

Some medical conditions may interact with Kepivance. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you are scheduled to receive chemotherapy within 24 hours


• if you have any non-blood-related cancer

Some MEDICINES MAY INTERACT with Kepivance. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Heparin because the effectiveness of Kepivance may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kepivance may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Kepivance:

Use Kepivance as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Kepivance is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Kepivance at home, carefully follow the injection procedures taught to you by your health care provider.


• Do not use Kepivance within 24 hours of certain chemotherapy because the effectiveness of Kepivance may be decreased.


• If you miss a dose of Kepivance, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Kepivance.

Important safety information:

• Because Kepivance works by increasing cell growth of skin and certain other tissues, it may increase growth of any tumor not related to the blood.


• Use Kepivance with caution in CHILDREN. Safety and effectiveness have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is unknown if Kepivance can cause harm to the fetus. If you become pregnant while taking Kepivance, discuss with your doctor the benefits and risks of using Kepivance during pregnancy. It is unknown if Kepivance is excreted in breast milk. If you are or will be breast-feeding while you are using Kepivance, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Kepivance:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in taste; joint pain; skin reactions (rash, irritation, redness, swelling, itching); tingling, numbness, prickling, or burning sensation around the mouth or on the skin; tongue thickening or discoloration.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Kepivance side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Kepivance:

Kepivance is usually handled and stored by a health care provider. If you are using Kepivance at home, store Kepivance as directed by your pharmacist or health care provider. Keep Kepivance out of the reach of children and away from pets.

General information:

• If you have any questions about Kepivance, please talk with your doctor, pharmacist, or other health care provider.


• Kepivance is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kepivance. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Kepivance resources

• Kepivance Side Effects (in more detail)
• Kepivance Use in Pregnancy & Breastfeeding
• Kepivance Drug Interactions
• Kepivance Support Group
• 0 Reviews for Kepivance - Add your own review/rating

• Kepivance Prescribing Information (FDA)


• Kepivance Consumer Overview


• Kepivance Monograph (AHFS DI)


• Kepivance Advanced Consumer (Micromedex) - Includes Dosage Information


• Palifermin Professional Patient Advice (Wolters Kluwer)

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